Blog
Latest articles, insights, and updates from the blog.
Contact Ketamine Resource
Send corrections, partnership questions, or advertising inquiries.
A Complete History of Ketamine: From Anesthetic to Antidepressant
Trace ketamine's history from its 1962 synthesis and Vietnam-era anesthesia to the 2000 depression discovery and 2019 FDA approval of Spravato.
Esketamine: The S-Enantiomer Behind Spravato
A glossary entry on esketamine, the S-enantiomer of ketamine marketed as Spravato, covering its pharmacology, FDA approval, and clinical significance.
Ketamine for Acute Suicidal Ideation: Rapid-Acting Intervention
How ketamine provides rapid relief from acute suicidal ideation, including clinical evidence, emergency department use, and the science behind its anti-suicidal effects.
Understanding Dissociation During Ketamine Treatment
A detailed guide to understanding dissociation during ketamine therapy, what it feels like, why it occurs, its therapeutic significance, and how clinicians manage it.
Key Ketamine Research Developments in 2025
Ketamine research highlights from 2025: TRD trials, BPL-003 phase 2a, measurement-based care data, telehealth outcomes, and what shifted in clinical practice.
FDA Esketamine (Spravato) Updates
A summary of the latest FDA regulatory actions, label updates, and clinical developments related to esketamine (Spravato) for depression treatment.
Ketamine Insurance Coverage: 2025 Trends and Developments
Ketamine insurance coverage in 2025: Spravato payer trends, off-label IV claim outcomes, prior-auth patterns, and what coverage gaps patients still face.
Telehealth Ketamine: Evolving Regulations
Telehealth ketamine prescribing rules in 2025: DEA Ryan Haight extensions, in-person visit triggers, dose limits, and the state variations patients hit.
Who Is a Good Candidate for Ketamine Therapy?
A guide to understanding who may benefit from ketamine therapy, including indications, screening criteria, contraindications, and how to determine if ketamine is right for you.
BDNF (Brain-Derived Neurotrophic Factor): Definition and Role in Ketamine Therapy
Learn what BDNF (Brain-Derived Neurotrophic Factor) is, how it supports brain health, and why it is central to ketamine's rapid antidepressant mechanism.
Oral and Sublingual Ketamine
Oral and sublingual ketamine: how lozenges and troches dose, bioavailability ranges, onset, at-home protocols, and where each fits versus IV or intranasal.
Ketamine-Assisted Psychotherapy (KAP): Integrating Therapy with Treatment
A comprehensive guide to ketamine-assisted psychotherapy, how KAP works, what a session looks like, therapeutic frameworks used, and evidence for enhanced outcomes.