Methods Articles
Latest articles, insights, and updates from the blog.
Racemic Ketamine vs Esketamine: Pharmacological Comparison
A detailed pharmacological comparison of racemic ketamine and esketamine (Spravato), covering efficacy, mechanisms, cost, access, and clinical decision-making.
Rectal Ketamine Administration: Uses in Pediatric and Palliative Care
An educational overview of rectal ketamine administration, including its pharmacokinetics, clinical applications in pediatric sedation and palliative care, and how it compares to other routes.
Oral and Sublingual Ketamine
A guide to oral and sublingual ketamine administration methods — how they differ from IV infusion, typical protocols, bioavailability, and practical considerations.
Intranasal Ketamine and Esketamine (Spravato)
A comprehensive guide to intranasal ketamine therapy, including the FDA-approved esketamine nasal spray Spravato — how it works, the REMS program, and clinical considerations.
Ketamine-Assisted Psychotherapy (KAP): Integrating Therapy with Treatment
A comprehensive guide to ketamine-assisted psychotherapy — how KAP works, what a session looks like, therapeutic frameworks used, and evidence for enhanced outcomes.
IV Ketamine Infusion
A detailed guide to intravenous ketamine infusion therapy — how it works, what to expect during treatment, protocols, and clinical considerations.
IV vs Oral vs Nasal Ketamine: Comparing Treatment Methods
A detailed comparison of IV infusion, oral/sublingual, and intranasal ketamine therapy methods covering effectiveness, cost, and convenience.
Intramuscular Ketamine Injection: Administration and Clinical Considerations
A detailed guide to intramuscular (IM) ketamine injection, including dosing, bioavailability, clinical applications, and how it compares to IV and other routes.
Continuous and Multi-Day Ketamine Infusions: Extended Protocols
An overview of continuous and multi-day ketamine infusion protocols — used primarily for chronic pain conditions, how they differ from standard single infusions, and clinical considerations.
Compounded Ketamine Formulations: Lozenges, Troches, and Creams
A guide to compounded ketamine formulations including lozenges, troches, nasal sprays, and topical creams — their uses, bioavailability, and clinical considerations.
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