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Key Ketamine Research Developments in 2025
Ketamine research highlights from 2025: TRD trials, BPL-003 phase 2a, measurement-based care data, telehealth outcomes, and what shifted in clinical practice.
FDA Esketamine (Spravato) Updates
A summary of the latest FDA regulatory actions, label updates, and clinical developments related to esketamine (Spravato) for depression treatment.
Ketamine Insurance Coverage: 2025 Trends and Developments
Ketamine insurance coverage in 2025: Spravato payer trends, off-label IV claim outcomes, prior-auth patterns, and what coverage gaps patients still face.
Telehealth Ketamine: Evolving Regulations
Telehealth ketamine prescribing rules in 2025: DEA Ryan Haight extensions, in-person visit triggers, dose limits, and the state variations patients hit.
Who Is a Good Candidate for Ketamine Therapy?
A guide to understanding who may benefit from ketamine therapy, including indications, screening criteria, contraindications, and how to determine if ketamine is right for you.
BDNF (Brain-Derived Neurotrophic Factor): Definition and Role in Ketamine Therapy
Learn what BDNF (Brain-Derived Neurotrophic Factor) is, how it supports brain health, and why it is central to ketamine's rapid antidepressant mechanism.
Oral and Sublingual Ketamine
Oral and sublingual ketamine: how lozenges and troches dose, bioavailability ranges, onset, at-home protocols, and where each fits versus IV or intranasal.
Ketamine-Assisted Psychotherapy (KAP): Integrating Therapy with Treatment
A comprehensive guide to ketamine-assisted psychotherapy — how KAP works, what a session looks like, therapeutic frameworks used, and evidence for enhanced outcomes.
Intranasal Ketamine and Esketamine (Spravato)
Intranasal ketamine and FDA-approved Spravato (esketamine): how dosing works, the REMS clinic visit, side effects, insurance coverage, and what to expect.
How Long Do Ketamine's Therapeutic Effects Last?
A detailed look at the duration of ketamine's antidepressant and analgesic effects, including factors that influence duration and strategies for maintaining benefit.
International Ketamine Research: Global Developments and Discoveries
A roundup of significant ketamine research from around the world, including clinical trials, regulatory developments, and scientific discoveries outside the United States.
Ketamine for PTSD
An examination of ketamine's role in treating post-traumatic stress disorder, including clinical research findings, proposed mechanisms, and treatment approaches.