research terms
Articles tagged with “research terms”
MADRS Score Explained in Ketamine Clinical Trials
MADRS is the 10-item scale most ketamine and esketamine trials use to measure depression severity. Learn how scoring, response, and remission work.
Ketamine Dissociation Meaning: A Clear Definition
Learn what ketamine dissociation means, why it happens during treatment, and how it differs from other effects. Explore the full glossary.
Dissociative Anesthetic: Definition, Drug Class & Examples
Plain-language guide to dissociative anesthetics, what the term means, which drugs belong to this class, and why ketamine is categorized this way.
Default Mode Network: How Ketamine Disrupts Depressive Thought Patterns
The default mode network (DMN) drives rumination in depression. Learn how ketamine disrupts DMN connectivity and why that matters for treatment.
Bioavailability: Understanding Ketamine Absorption by Route
Bioavailability shows how much ketamine actually reaches the bloodstream. See how it ranges from 100% IV to 17-24% oral and what that means for dosing.
Synaptogenesis: How Ketamine Promotes New Synaptic Connections
Synaptogenesis is the formation of new synapses. Learn how ketamine triggers rapid synapse growth through NMDA, BDNF, and mTOR signaling.
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