neuroscience
Articles tagged with “neuroscience”
How Ketamine Works in the Brain
An in-depth look at ketamine's mechanism of action — NMDA receptor antagonism, glutamate signaling, BDNF release, and the promotion of neuroplasticity.
Ketamine and the Opioid System: How Ketamine Interacts with Opioid Receptors
An in-depth exploration of ketamine's interactions with the opioid receptor system, the scientific debate over whether opioid activity contributes to its antidepressant effects, and clinical implications.
Ketamine and Neuroinflammation: Anti-Inflammatory Mechanisms
An exploration of ketamine's anti-inflammatory properties, the link between neuroinflammation and depression, and how these mechanisms contribute to therapeutic effects.
Ketamine and Epigenetics: How Ketamine May Alter Gene Expression
An exploration of emerging research on ketamine's epigenetic mechanisms, including histone modification, DNA methylation changes, and how these processes may contribute to lasting antidepressant effects.
How Ketamine Works: A Detailed Scientific Explanation
An in-depth exploration of ketamine's mechanism of action — from NMDA receptor blockade to glutamate surge, AMPA activation, BDNF release, and rapid synaptogenesis.
How Ketamine Works in the Brain: A Complete Neuroscience Guide
An in-depth exploration of ketamine's mechanism of action at the molecular, cellular, and network levels — from NMDA receptor blockade and the glutamate surge to BDNF-driven synaptogenesis and default mode network modulation.
Synaptogenesis: How Ketamine Promotes New Synaptic Connections
A definition of synaptogenesis — the formation of new synapses — and an explanation of how ketamine rapidly triggers this process to produce antidepressant effects.
NMDA Receptor
A comprehensive definition and explanation of the NMDA receptor — its role in the brain, its relevance to ketamine therapy, and why it matters for mental health treatment.
Neuroplasticity
What neuroplasticity means, how the brain rewires itself, and why neuroplasticity is central to understanding ketamine's rapid antidepressant effects.
Glutamatergic System: The Excitatory Signaling Network Behind Ketamine's Effects
An overview of the glutamatergic system — the brain's primary excitatory neurotransmitter network — and its central role in how ketamine produces rapid antidepressant effects.
Glutamate: The Excitatory Neurotransmitter Central to Ketamine's Action
Understand glutamate, the brain's primary excitatory neurotransmitter, its role in neural signaling, and why it is fundamental to how ketamine works.
GABA (Gamma-Aminobutyric Acid): The Brain's Primary Inhibitory Neurotransmitter
A definition of GABA — the brain's main inhibitory neurotransmitter — and its relationship to ketamine's mechanism of action and therapeutic effects.
BDNF (Brain-Derived Neurotrophic Factor): Definition and Role in Ketamine Therapy
Learn what BDNF (Brain-Derived Neurotrophic Factor) is, how it supports brain health, and why it is central to ketamine's rapid antidepressant mechanism.
AMPA Receptor: Its Role in Ketamine's Antidepressant Effect
A glossary entry on the AMPA receptor, explaining what it is, how it functions, and why its activation is essential to ketamine's rapid antidepressant mechanism.
How Ketamine Works: Science FAQ
Answers to frequently asked questions about ketamine's mechanism of action, how it differs from other treatments, and the science behind its antidepressant effects.
Ready to learn more?
Explore our comprehensive guides and tools to help you navigate your ketamine therapy journey.