Ketamine Treatment Methods
Compare IV, intranasal, sublingual, oral, and clinic-based ketamine treatment methods with practical context on monitoring, onset, access, and tradeoffs.
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Begin with method overviews, then use comparison articles for route-specific tradeoffs and safety considerations.
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Featured
3 articles
Rectal Ketamine Administration: Uses in Pediatric and Palliative Care
An educational overview of rectal ketamine administration, including its pharmacokinetics, clinical applications in pediatric sedation and palliative care, and how it compares to other routes.
Racemic Ketamine vs Esketamine: Pharmacological Comparison
Racemic ketamine vs esketamine pharmacology: NMDA binding, half-life, dose equivalence, side effect profile, cost per session, and clinical decision points.
IV vs Oral vs Nasal Ketamine: Comparing Treatment Methods
IV, oral/sublingual, and intranasal ketamine compared by bioavailability, onset, monitoring time, cost per session, and what each route is typically used for.
Rectal Ketamine Administration: Uses in Pediatric and Palliative Care
An educational overview of rectal ketamine administration, including its pharmacokinetics, clinical applications in pediatric sedation and palliative care, and how it compares to other routes.
Racemic Ketamine vs Esketamine: Pharmacological Comparison
Racemic ketamine vs esketamine pharmacology: NMDA binding, half-life, dose equivalence, side effect profile, cost per session, and clinical decision points.
IV vs Oral vs Nasal Ketamine: Comparing Treatment Methods
IV, oral/sublingual, and intranasal ketamine compared by bioavailability, onset, monitoring time, cost per session, and what each route is typically used for.
Compounded Ketamine Formulations: Lozenges, Troches, and Creams
Compounded ketamine lozenges, troches, nasal sprays, and creams: how compounding pharmacies prepare each, dose ranges, bioavailability, and quality checks.
Intramuscular Ketamine Injection: Administration and Clinical Considerations
Intramuscular (IM) ketamine injection explained: typical dose ranges, bioavailability, onset, clinical use cases, and how IM compares to IV and intranasal.
Oral and Sublingual Ketamine
Oral and sublingual ketamine: how lozenges and troches dose, bioavailability ranges, onset, at-home protocols, and where each fits versus IV or intranasal.
Intranasal Ketamine and Esketamine (Spravato)
Intranasal ketamine and FDA-approved Spravato (esketamine): how dosing works, the REMS clinic visit, side effects, insurance coverage, and what to expect.
Ketamine-Assisted Psychotherapy (KAP): Integrating Therapy with Treatment
A comprehensive guide to ketamine-assisted psychotherapy — how KAP works, what a session looks like, therapeutic frameworks used, and evidence for enhanced outcomes.
IV Ketamine Infusion
IV ketamine infusion therapy explained: standard 0.5 mg/kg protocol, session length, monitoring, side effects during infusion, and the typical 6-session series.
Continuous and Multi-Day Ketamine Infusions: Extended Protocols
Continuous and multi-day ketamine infusions for chronic pain: extended dosing protocols, indications, monitoring, and how they differ from single sessions.